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Longevity · Recovery

Is your growth-hormone axis the bottleneck?

A composite score across four everyday signals linked to GH output: sleep depth, recovery, daytime energy, and (optionally) IGF-1. It’s an educational way to think about your habits. It can’t measure your hormones or diagnose anything.

~2 minutes No labs required Optional IGF-1 input
Most
GH release happens during deep sleep
After 30
GH output declines roughly 1-2% per year
4 signals
Sleep, recovery, energy, and IGF-1

Profile inputs

yrs
hrs
ng/mL

Fill in your profile to see a GH-axis score across sleep, recovery, energy, and (optionally) IGF-1.

Your score is educational only. If you have concerns, talk to a licensed provider.

Score interpretation

Where your score lands, and what it means.

Score range is 0-30. The bands aren’t diagnostic. They’re a structured way to think about your sleep, recovery, and energy habits.

25-30
Strong pillars

Sleep, recovery, and energy look solid. Keep doing what you’re doing and focus on consistent habits.

18-24
Moderate

Some pillars are slipping. Start with sleep, training, and recovery. Consider talking to a licensed provider if concerns persist.

10-17
Several pillars low

Several pillars are low. Worth discussing with a licensed provider alongside sleep and lifestyle work.

0-9
Most pillars low

Sleep, recovery, and energy all scored low. Consider talking to a licensed provider about your symptoms and health history. This score is not a diagnosis.

The lifetime view

Your GH axis, across a lifetime.

Growth-hormone output peaks in your late teens and declines steadily, roughly 1-2% a year after 30. Drag the slider to see how much the axis shifts with age, then calculate your score above to plot where your own pillars land.

40
At 40, average GH output is about 86% of its late-teen peak.
The four pillars

What this score actually measures.

Growth hormone is hard to measure directly, serum GH is pulsatile and unreliable. The downstream tissue-level effects are the practical signal.

Sleep depth

The most consistent GH signal

Much of daily GH release happens during deep, slow-wave sleep, so sleep depth, wake-ups, and how rested you feel are practical everyday signals to track. Many things besides GH affect sleep.

Daily recovery

Tissue repair speed

Growth hormone plays a role in tendon, ligament, and connective-tissue repair. Slow recovery from normal daily activity and recurring soft-tissue issues can be signs of age-related GH-axis decline in adults over 40. Many other factors affect recovery too.

Daytime energy

Energy & recovery capacity

The GH axis supports daytime energy, recovery, and sleep-driven restoration. Lower energy has many possible causes, so this pillar is a rough signal only.

IGF-1 (optional)

The downstream lab marker

IGF-1 is the longer-acting messenger that mediates most of GH’s peripheral effects. Reference ranges vary by age, sex, and lab, and only a clinician can interpret your result. Add a recent value if you have one; the tool uses it as a rough input only.

How the GH axis works, and why it fades

Growth hormone is released in pulses, mostly during deep, slow-wave sleep. Your pituitary sends the signal, your liver responds by producing IGF-1, and that downstream marker is what a blood test actually measures. It’s the system behind overnight tissue repair, recovery, and how rested you feel the next day.

Output peaks in your late teens and then declines steadily, roughly 1-2% per year after age 30. By your 40s and 50s, total daily GH can be a fraction of what it once was, which is part of why sleep feels lighter and recovery takes longer even when nothing else has changed.

What actually moves it

There are also provider-guided options that work upstream, such as sermorelin, a GHRH peptide that signals your own pituitary to release GH rather than replacing the hormone directly. Whether anything like that is appropriate for you is a decision a U.S.-licensed provider makes after reviewing your health history. Compounded medications are not FDA-approved.

This score is not a diagnosis. It can’t tell you your hormone levels or whether you need treatment. A licensed provider decides what, if anything, is appropriate, and may ask for lab work first.

Your axis is worth understanding.

Your score is educational, not a diagnosis. If you’re curious about sermorelin, a U.S.-licensed provider can review your health history and decide whether it’s appropriate for you.

Learn about sermorelin →
References

The science behind the numbers.

This is a structured, educational way to think about the growth-hormone axis using downstream signals like sleep and recovery. The bands are not diagnostic; GH status is assessed by a clinician. It is not medical advice.

Educational purposes only. The GH Optimization Score provides educational estimates based on published clinical formulas and peer-reviewed research. It is not medical advice, does not constitute a prescription, and is not a substitute for evaluation by a licensed clinician. All medical decisions, including any treatment, medication, or dosing recommendations, are made exclusively by an independent, U.S.-licensed provider after an individual evaluation through ShyftMD's online visit.
Methodology & Sources Click here for the formulas, datasets, and peer-reviewed studies behind this tool View details ↓Hide ↑

How this tool calculates

Your answers are scored across four pillars: sleep (0-9), recovery (0-9), daytime energy (0-6), and IGF-1 (0-6, or a neutral 3 if you skip it), for a total of 0-30. The bands and the lifetime chart are a simple educational model, not a validated clinical scale.

Peer-reviewed sources

  1. 1.Bidlingmaier M, Friedrich N, Emeny RT, et al. Reference intervals for insulin-like growth factor-1 (IGF-I) from healthy adults: results from the Berlin Aging Study II. J Clin Endocrinol Metab. 2014;99(5):1712-1721.
  2. 2.Yuen KCJ, Biller BMK, Radovick S, et al. American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care. Endocr Pract. 2019;25(11):1191-1232.

Important. This tool is provided for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The tool does not prescribe medication, recommend specific dosing, or substitute for clinical evaluation. Compounded medications referenced anywhere on this site are not FDA-approved; the FDA does not verify the safety, effectiveness, or quality of compounded drugs. Treatment decisions are made only by a licensed U.S. provider after an individual evaluation.

Compounded medication disclaimer

ShyftMD offers compounded sermorelin and compounded semaglutide, prescribed by independent, U.S.-licensed providers through Wasef Health, PC when they decide it is appropriate. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. ShyftMD is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.